Manufacture and sale of lactic acid bacteria Manufacture and sale of food
Effects
The effects of lactic acid bacteria
Effect 1: Nano-type lactic acid bacteria® nEF: Prevents influenza virus infection
Influenza rages every year, but experiments have shown that nano-sized lactic acid bacteria are effective in preventing influenza infection. Below is the non-nano-sized version and the experimental report.
Experiment on the effectiveness of preventing influenza infection
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Exam Content
Mice were orally administered nano-type lactic acid bacteria (nano-treated E.faecalis KH strain, hereafter referred to as nEF) or non-nano-type lactic acid bacteria (non-nano-treated E.faecalis KH strain, hereafter referred to as non-nano-treated nEF) every day from 7 days before infection with influenza A virus to 14 days after infection, and the virus amount in bronchoalveolar lavage fluid (hereafter referred to as BALF) (3 days after infection), neutralizing antibody titer, and virus-specific IgA (14 days after infection) were compared.
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Test results
The constipation state was evaluated using the Constipation Assessment Scale (CAS-MT) before and one week after nEF intake. A higher CAS-MT value indicates a more constipated state. The test results showed that the average CAS-MT value one week after nEF intake compared to before intake decreased by 66.7% (7.6 ⇒ 2.5), indicating that nEF intake improved bowel movements. A significant difference was also observed in the CAS-MT values before and after intake (Figures 1 and 2).
As shown in Figures 3 and 4, the neutralizing antibody titers and virus-specific IgA levels in BALF were high in the nEF-treated group.
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Commentary
Taking nEF was found to have a protective effect against influenza virus infection. The effect was dose-dependent. Furthermore, nano-processing of lactic acid bacteria is important because the effect is enhanced by nano-processing.
