Manufacture and sale of lactic acid bacteria Manufacture and sale of food
Effects
The effects of lactic acid bacteria
Mechanism and conditions under which lactic acid bacteria work
Biogenics theory has different conditions than the conventional probiotics and prebiotics. Through various experiments, we have discovered the conditions that make lactic acid bacteria work well.
How lactic acid bacteria work
Cytokine production is a danger signal that a foreign substance has been introduced into the organism.
The intestines are covered with countless villi, but there are also areas without villi, called "Peyer's patches." Peyer's patches include:
Particles such as lactic acid bacteria that enter the intestinal tract are taken up into the body through M cells present in Peyer's patches.
The ingested particles are recognized as a danger signal by the body's "dendritic cells" and "macrophages," and are ingested and broken down.
Whether the lactic acid bacteria are alive or dead is irrelevant
Dead bacteria are also important
Because biogenics does not involve intestinal flora, it is not so important whether the bacteria are alive or dead; what is important are the substances produced by lactic acid bacteria, including dead bacteria: metabolic products and bacterial components.
In an experiment demonstrating this, mice were fed food containing pasteurized fermented milk, and the results showed that the lifespan of mice fed 14% pasteurized fermented milk was 8% longer than that of mice fed regular food or 14% milk. Moreover, it was reported that the amount of bifidobacteria in the intestines of the pasteurized lactic acid bacteria group was twice as high as that of the other two groups.
The smaller the lactic acid bacteria, the easier it is to absorb.
Smaller lactobacilli are more easily absorbed by the body.
Whether they are alive or dead does not matter, but experimental research has revealed that the smaller the lactic acid bacteria are, the better they work, and that those under 20 micrometers are even more effective.
The figure on the right shows the relationship between lactic acid bacteria particle size and IL-12 production induction function, and it can be seen that the smaller the lactic acid bacteria particles, the greater the IL-12 production induction function.
What is IL-12 production induction function?
A potent regulator of cellular immunity, inducing the production of IFNγ by NK and T cells
The more lactic acid bacteria there are, the more effective it is.
The ideal is 1 trillion lactic acid bacteria per day
To get the most out of lactic acid bacteria, it is important to consume a large amount. According to Dr. Tatsuhiko Suga, a leading researcher in lactic acid bacteria, it is necessary to eat 1 trillion lactic acid bacteria every day to maintain good health. This is also evident from the fact that the results of experiments on the effectiveness of lactic acid bacteria are dose-dependent.
Homemade yogurt is said to have 80 times the amount of lactic acid bacteria as commercially available yogurt. Tokyo Foods has a track record of producing kits for making homemade yogurt, and has a wide range of products that allow you to get a large amount of lactic acid bacteria from a small amount.