Manufacture and sale of lactic acid bacteria Manufacture and sale of food
The effects of lactic acid bacteria
Effects
The 21st century is the era of "biogenics"
Lactobacilli were first studied in earnest in 1857. Since then, various types of lactobacilli have been discovered, and it is now known that they live in the human intestine.
In the 21st century, a new concept of “biogenics” has emerged. This biogenics, which acts directly on the whole body, is the latest lactobacilli theory that is now attracting the most attention.
The main hypothesis of lactic acid bacteria up until the 20th century was that "lactic acid bacteria live and multiply"
The theory that live lactic acid bacteria work through the intestinal flora to produce beneficial effects on the body
Prior to biogenics , the concepts of "probiotics" and "prebiotics" were proposed, in which lactic acid bacteria act through the intestinal flora.
Probiotics describes the function of live microorganisms that affect human health, while prebiotics are foods that promote the growth of good bacteria in the intestines and balance the intestinal flora (put simply, foods that serve as food for the good bacteria).
Probiotics
Improves intestinal environment through the action of live bacteria
Prebiotics
Improve the intestinal environment by ingesting food ingredients that serve as food for intestinal bacteria
Both are based on the hypothesis that live lactic acid bacteria act on the body via the intestines (intestinal flora).
In the 20th century, the "probiotics" and "prebiotics" theories were mainstream.
But a contradiction emerges
In 1989, this theory was defined as "a substance that has a beneficial effect on animals by controlling their intestinal flora," and it quickly attracted the attention of pharmaceutical companies and lactic acid bacteria drink manufacturers, who used the phrase to promote their products. However, as more experiments were conducted, rather than proving this hypothesis, facts that contradicted it became clear.
The fact that lactic acid bacteria cannot survive and grow in the intestines
Lactic acid bacteria cannot grow in the harsh environment of the intestine.
It is difficult to verify this hypothesis that lactic acid bacteria can live and multiply. In the first place, in the intestines, where various bacteria are crowded together, it is difficult for lactic acid bacteria to live and function, let alone multiply.
"They live and multiply" has yet to be proven to this day.
The "lactic acid bacteria increase theory" proposed by a major manufacturer and believed by many people has remained unproven to this day. This experiment shows the danger of conducting verification experiments to prove a hypothesis.
Reflection on hypothesis-based verification experiments
Believing in the "live and multiply" hypothesis, he devoted himself to experiments to prove it
When I was a researcher at a major lactobacilli beverage manufacturer, I believed that “if you drink live lactobacilli, those lactobacilli will live and increase in your intestines. I hypothesized that if lactobacilli increased in the intestines, lactobacilli would produce lactic acid, which would reduce bad bacteria and increase good bacteria such as lactobacilli and bifidobacteria, and I spent all my time doing experiments to prove this. My experiment was, of course, to prove that the lactobacilli I drank increased, and also to expect the result that the intestinal microflora would replace the predominance of good bacteria.
This experiment was conducted by 15 researchers who analyzed stool and urine samples with the help of volunteers at a rate of 3 times/week over a period of 3 months.
However, this experiment ended with the result that even if fresh live lactobacilli were consumed, the consumed lactobacilli did not increase in the intestines, the intestinal flora did not change, and there were no chemical changes in the intestinal contents at all.
The conclusion of this study was that, contrary to the manufacturer's expectations, “even if you drink live lactobacilli, the bacteria do not increase in your intestines, nor do they have any effect on the intestinal microflora.
Professor Tatsuhiko Suga
Biogenics” proves the function of lactic acid bacteria
So what is the theory behind how lactic acid bacteria work in the body? The new concept of "biogenics" explains this. Biogenics, which acts directly on the entire body, is the latest lactic acid bacteria theory that is currently attracting the most attention, and it is said that biogenics is the theory that elucidates the function of lactic acid bacteria.
Lactobacilli work directly on the body without involving the intestinal flora
to the body directly without involving the intestinal flora.
Biogenics is different from "probiotics" and "prebiotics."
The idea is that lactic acid bacteria send signals to the body without going through the intestinal flora, and bring about various functions in the body. Because it is direct, it can perform various beneficial functions.
Whether the lactic acid bacteria are alive or dead is irrelevant
Until now, it was assumed that lactic acid bacteria were alive and multiplying, but since they can function even when dead, it is thought that it is not so important whether they are alive or dead, and that the substances produced by lactic acid bacteria, including dead bacteria, namely metabolic products and bacterial components, are important. Rather, it has become clear that size is more important.
Tokyo Foods' lactic acid bacteria are based on biogenics theory and directly have a health benefit to the body by consuming a large amount of dead bacteria.
Lactic acid bacteria based on Tokyo Food's Biogenics
The effect of lactic acid bacteria in biogenics theory
Influenza Virus
Effect on
Effectiveness against norovirus
Anti-inflammatory effects
Effect on NK activity
Improves constipation
How lactic acid bacteria work in Biogenics and important conditions
